1.
Physiology (Bethesda)
; 38(4): 0, 2023 07 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36976098
RESUMO
The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) inflammatory pathway is a component of the innate immune system that recognizes cytosolic nucleic acids. The pathway has been implicated in several processes including aging, autoinflammatory conditions, cancer, and metabolic diseases. The cGAS-STING pathway represents a promising therapeutic target in a variety of chronic inflammatory diseases.